異位性皮膚炎,普遍會在經前惡化,特別是在月經來潮前一周:系統性文獻回顧
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本篇研究,“Impact of the menstrual cycle on exacerbations of atopic dermatitis: a systematic review”,請見這裡(外部網站),期刊摘要如下:
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin condition. Patients with AD often report experiencing cutaneous deterioration associated with certain points of their menstrual cycle. Despite this, the literature surrounding this topic remains sparse.
To summarize and compare recent publications considering the association between the different stages of the menstrual cycle and exacerbations of AD.
A literature review was conducted following the PRISMA guidelines using Ovid MEDLINE, Embase, Cochrane Library, PubMed and Web of Science. Search terms and variations on these terms included ‘menstruation’, ‘eczema’ and ‘atopic dermatitis’. A minimum of two authors independently screened each abstract and reviewed the full text for inclusion. Sixteen studies were included.
All articles consistently acknowledged premenstrual deterioration in the control of AD, typically occurring in the week before menstruation. Our results highlight that premenstrual exacerbation of AD is a well-recognized phenomenon, typically occurring in the week before menstruation.
Existing studies are of a low quality, and we identified minimal evidence on treatment strategies for premenstrual exacerbations of AD.
Further large-scale studies are needed to explore treatment options for these patients, such as hormonal therapies.
原始論文
Impact of the menstrual cycle on exacerbations of atopic dermatitis: a systematic review(外部網站)
McSwiney NT, Hutchison E, Moran R, Phillips A, et al. Clinical and Experimental Dermatology. 2025;50(9):1748-1754. doi:10.1093/ced/llaf153
論文摘要(Google 翻譯)
以下為 Google 翻譯,並校正明顯錯誤,僅供參考,內容以英文原文為準。
月經週期對異位性皮膚炎惡化的影響:系統性回顧
異位性皮膚炎(AD)是一種慢性搔癢性發炎性皮膚病。AD 患者常表示皮膚狀況會在月經週期的某些時間點惡化。儘管如此,這個主題的相關文獻仍然很少。
彙整並比較近期探討月經週期各階段與 AD 惡化之關聯的文獻。
依 PRISMA 指引,以 Ovid MEDLINE、Embase、Cochrane Library、PubMed 與 Web of Science 進行文獻回顧。檢索詞及其變化包括「月經」、「濕疹」與「異位性皮膚炎」。每篇摘要至少由兩位作者獨立篩選,並審閱全文決定是否納入。共納入 16 項研究。
所有文章一致指出 AD 控制會在經前惡化,通常發生在月經前一週。我們的結果凸顯 AD 經前惡化是廣為人知的現象,通常發生在月經前一週。
現有研究品質偏低,且我們發現關於 AD 經前惡化之治療策略的證據極少。
需要更多大規模研究,探討這些患者的治療選項,例如荷爾蒙治療。
異位性皮膚炎,期刊研究,請看這裡。
期刊研究整理,請見這裡。
異位性皮膚炎,中醫經方的治療實例,請見這裡。
原文發表於 作者部落格(舊部落格)。