異位性皮膚炎、乾癬、痤瘡患者，不只皮膚，連腸道亦呈現共生菌叢失衡

本篇研究，Gut–Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions，請見這裡（外部網站）。

The microbiome plays an important role in a wide variety of skin disorders. Not only is the skin microbiome altered, but also surprisingly many skin diseases are accompanied by an altered gut microbiome. The microbiome is a key regulator for the immune system, as it aims to maintain homeostasis by communicating with tissues and organs in a bidirectional manner. Hence, dysbiosis in the skin and/or gut microbiome is associated with an altered immune response, promoting the development of skin diseases, such as atopic dermatitis, psoriasis, acne vulgaris, dandruff, and even skin cancer. Here, we focus on the associations between the microbiome, diet, metabolites, and immune responses in skin pathologies. This review describes an exhaustive list of common skin conditions with associated dysbiosis in the skin microbiome as well as the current body of evidence on gut microbiome dysbiosis, dietary links, and their interplay with skin conditions. An enhanced understanding of the local skin and gut microbiome including the underlying mechanisms is necessary to shed light on the microbial involvement in human skin diseases and to develop new therapeutic approaches.

原始論文

Gut–Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions（外部網站）

De Pessemier B, Grine L, Debaere M, Maes A, et al. Microorganisms. 2021;9(2):353. doi:10.3390/microorganisms9020353

上方英文摘要引自原始論文，依 CC BY 4.0（外部網站） 授權轉載。

論文摘要（Google 翻譯）

以下為 Google 翻譯，並校正明顯錯誤，僅供參考，內容以英文原文為準。

腸道-皮膚軸：微生物失調與皮膚狀況之間相互關係的最新知識

微生物組在多種皮膚疾病中發揮重要作用。不僅皮膚微生物組發生了改變，而且令人驚訝的是，許多皮膚病都伴隨著腸道微生物組的改變。微生物組是免疫系統的關鍵調節因子，因為它的目的是透過與組織和器官的雙向溝通來維持體內平衡。因此，皮膚和/或腸道微生物組的菌叢失調與免疫反應的改變有關，促進皮膚疾病的發展，如異位性皮膚炎、乾癬、尋常性痤瘡、頭皮屑，甚至皮膚癌。在這裡，我們將重點放在皮膚病理中微生物組、飲食、代謝物和免疫反應之間的關聯。這篇綜述詳盡地列出了與皮膚微生物群失調相關的常見皮膚病，以及有關腸道微生物群失調、飲食聯繫及其與皮膚狀況相互作用的現有證據。有必要加強對局部皮膚和腸道微生物組（包括潛在機制）的了解，以闡明微生物與人類皮膚病的關係並開發新的治療方法。

異位性皮膚炎，中醫經方的治療實例，請見這裡。

乾癬，中醫經方的治療實例，請見

這裡。

青春痘，中醫經方的治療實例，請見

這裡（舊部落格）。

期刊研究整理，請見這裡。

乾癬，期刊研究，請看這裡。